About Loxo@Lilly:
Loxo@Lilly aims to create medicines that make life better for all those affected by cancer around the world. Bringing together the focus and spirit of a biotech with the scale, resources, and heritage of Lilly, our team is focused on rapidly delivering impactful new medicines for people with cancer. Our approach centers on creating oncology medicines that unequivocally show early signs of clinical activity and will matter to patients. We intend to curate a balanced pipeline of medicines, either internally or externally discovered, with the potential to treat cancer with dramatic effect. Loxo@Lilly was created in December 2019, combining the Lilly Oncology organization and Loxo Oncology, which was acquired by Lilly in early 2019. Loxo@Lilly is a global organization with team members in Louisville, Colorado; Indianapolis, Indiana; New York City, New York; San Diego, California; South San Francisco, California; Stamford, Connecticut; and Madrid, Spain.
We are looking for a highly motivated Scientist Consultant with background in molecular biology and protein biochemistry to join our Antibody Discovery Group in South San Francisco. The Scientist Consultant will be responsible for supporting molecular biology efforts devoted to generating antibody/protein expression constructs and library generation. This individual will work closely with members of the Antibody Discovery Team to support Large Molecule therapeutic programs.
Roles and Responsibilities of the Position:
- Clone recombinant antibody and protein expression constructs, including sample preps and high-throughput sequence analysis
- Support antibody discovery and engineering campaigns by constructing in vitro display libraries (phage and yeast)
- Perform various scales of DNA preps for mammalian cell transfection to produce recombinant antibodies and proteins
- Use of liquid handlers to automate sample preparation and storage procedures
- Organize DNA and glycerol bacteria samples for distribution and proper storage
- Work collaboratively with Large Molecule functional teams to ensure materials are delivered on time
- Demonstrate collection and thorough analysis of data, and update Electronic Notebook records
Required Qualifications and Preferred Background:
- Required:
- BS in Biology, Biochemistry, Biomedical Engineering, Cancer Biology, Pharmacology, or related field with 0-2 years of experience working in an academic or industry laboratory setting.
- Level commensurate with education and experience
- Ideal candidate will also have:
- Experience in various molecular biology techniques, including molecular cloning including Gibson assembly , site-directed mutagenesis, DNA purification, and phage or yeast display library construction
- Experience in using bioinformatics and molecular biology software to analyze DNA and protein sequences for sequencing confirmation, cluster analysis, and design of de-novo expression constructs
- Highly motivated, fast learner with strong organization skills to effectively present data and summary of results, and ability to solve problems
- Excellent written and verbal communication skills
- Strong interpersonal skills
Physical Demands/Travel:
The physical demands of this job are consistent with lab environment/light office duties.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
Work Environment:
This position’s work environment is in an office
The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform the role and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo@Lilly (Eli Lilly and Company) is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
As a condition of employment with Eli Lilly and Company and its subsidiaries in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide proof of vaccination satisfactory to the company (subject to applicable law).
Loxo@Lilly (Eli Lilly and Company) is committed to help individuals with disabilities participate in the workforce and ensure equal opportunity to compete for jobs. If you are an individual with a disability and require a reasonable accommodation to participate in the application process for positions at Loxo, please email loxoaccommodation@loxooncology.com for further assistance. Please note, this email address is intended for use to request an accommodation as a part of the application process. Any other correspondence will not receive a response.
