Research Associate I/II/Sr, Cell Biology

Company Summary:

FL87, Inc. is a privately held, early-stage biotechnology company developing a novel approach to gene therapy that can address currently untreatable diseases.

FL87 was founded by Flagship Pioneering, an innovation enterprise that conceives, creates, resources, and grows first-in-category life sciences companies. Flagship Pioneering has created over 100 groundbreaking companies over the past twenty years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna (MRNA), Syros Pharmaceuticals (SYRS), Seres Therapeutics (NASDAQ:MCRB), Generate Biomedicines, Tessera Tx, Evelo Biosciences (EVLO), and Indigo Agriculture.

Position Summary:

We are searching for an experienced and enthusiastic Research Associate to support the development of novel nucleic acid therapeutics. We are looking for an individual who is excited to innovate a new class of programmable medicines. This individual will be responsible for hands-on cell biology work in the lab and is expected to bring scientific rigor and intellectual curiosity to their role. This individual will have the opportunity to work in a dynamic and fast-paced entrepreneurial environment as part of a highly collaborative and rapidly growing team.

Key Responsibilities:

• Maintaining and optimizing primary and immortalized cell lines
• Delivering nucleic acids to cells with methods such as lipofection, electroporation, nucleofection, and viral transduction
• Performing cell-based and nucleic acid-based assays such as flow cytometry, confocal microscopy, FISH, and RT-qPCR
• Performing biochemical fractionation, nucleic acid isolation, and downstream functional genomics analyses
• Designing, executing, troubleshooting, and analyzing experimental methods and findings
• Effectively communicating experimental methods and findings in oral and written formats
• Working independently and collaboratively in a multidisciplinary team environment

Qualifications:

• B.Sc. or M.S. in Biology or related field; ideally with 1+ years of experience
• Significant experience and comfort with mammalian cell culture
• Experience with flow cytometry and RT-qPCR is required
• Experience with single molecule FISH, viral transduction, cellular fractionation is preferred
• Handling multiple projects simultaneously to meet project timelines
• Track record of careful and thoughtful execution of experiments and trouble-shooting
• Strong communication and interpersonal skills
• Strong organizational, analytical, and problem-solving skills
• Self-motivation and ability to thrive in a fast-paced, multidisciplinary, and rapidly growing biotech environment